Cargando…

The HPV-16 E7 oncoprotein induces centriole multiplication through deregulation of Polo-like kinase 4 expression

BACKGROUND: Infection with high-risk human papillomaviruses (HPVs) such as HPV-16 is intimately associated with squamous cell carcinomas (SCCs) of the anogenital tract and a subset of oropharyngeal carcinomas. Such lesions, including pre-invasive precursors, frequently show multipolar mitoses and an...

Descripción completa

Detalles Bibliográficos
Autores principales:	Korzeniewski, Nina, Treat, Benjamin, Duensing, Stefan
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	BioMed Central 2011
Materias:	Short Communication
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3120798/ https://www.ncbi.nlm.nih.gov/pubmed/21609466 http://dx.doi.org/10.1186/1476-4598-10-61

Ejemplares similares

Daughter Centriole Elongation Is Controlled by Proteolysis
por: Korzeniewski, Nina, et al.
Publicado: (2010)

Chemical Probe for Imaging of Polo-like Kinase 4 and Centrioles
por: Salim, Aleksandar, et al.
Publicado: (2023)

Autophosphorylation of Polo-like Kinase 4 and Its Role in Centriole Duplication
por: Sillibourne, James E., et al.
Publicado: (2010)

Polo-like kinase 4 controls centriole duplication but does not directly regulate cytokinesis
por: Holland, Andrew J., et al.
Publicado: (2012)

Phase separation of Polo-like kinase 4 by autoactivation and clustering drives centriole biogenesis
por: Park, Jung-Eun, et al.
Publicado: (2019)

Balancing the scales: fine-tuning Polo-like kinase 4 to ensure proper centriole duplication
por: Ryniawec, John M., et al.
Publicado: (2022)

Role of Polo-like Kinases Plk1 and Plk4 in the Initiation of Centriole Duplication—Impact on Cancer
por: Hoffmann, Ingrid
Publicado: (2022)

Polo-Like Kinase 2-Dependent Phosphorylation of NPM/B23 on Serine 4 Triggers Centriole Duplication
por: Krause, Annekatrin, et al.
Publicado: (2010)

Polo-like kinase 4 transcription is activated via CRE and NRF1 elements, repressed by DREAM through CDE/CHR sites and deregulated by HPV E7 protein
por: Fischer, Martin, et al.
Publicado: (2014)

Ana1 helps recruit Polo to centrioles to promote mitotic PCM assembly and centriole elongation
por: Alvarez-Rodrigo, Ines, et al.
Publicado: (2021)

Centriole foci persist in starfish oocytes despite Polo-like kinase 1 inactivation or loss of microtubule nucleation activity
por: Pierron, Marie, et al.
Publicado: (2020)

Polo-like kinase 4 homodimerization and condensate formation regulate its own protein levels but are not required for centriole assembly
por: Ryniawec, John M., et al.
Publicado: (2023)

STIL binding to Polo-box 3 of PLK4 regulates centriole duplication
por: Arquint, Christian, et al.
Publicado: (2015)

HPV16 AND EXPRESSION OF PROTEIN P16(INK4A) AND E7 ONCOPROTEIN IN COLORECTAL CARCINOMA
por: PICANÇO-JUNIOR, Olavo Magalhães, et al.
Publicado: (2022)

Polo-like kinase in trypanosomes: an odd member out of the Polo family
por: Kurasawa, Yasuhiro, et al.
Publicado: (2020)

DNA virus oncoprotein HPV18 E7 selectively antagonizes cGAS‐STING‐triggered innate immune activation
por: Lou, Meng, et al.
Publicado: (2022)

Serum HPV16 E7 Oncoprotein Is a Recurrence Marker of Oropharyngeal Squamous Cell Carcinomas
por: Oton-Gonzalez, Lucia, et al.
Publicado: (2021)

Activation of Src, Fyn and Yes non-receptor tyrosine kinases in keratinocytes expressing human papillomavirus (HPV) type 16 E7 oncoprotein
por: Szalmás, Anita, et al.
Publicado: (2013)

Putting a bit into the polo-box domain of polo-like kinase 1
por: Park, Jung-Eun, et al.
Publicado: (2015)

An RNA Aptamer Provides a Novel Approach for the Induction of Apoptosis by Targeting the HPV16 E7 Oncoprotein
por: Nicol, Clare, et al.
Publicado: (2013)

Preparation, Characterization and Diagnostic Valuation of Two Novel Anti-HPV16 E7 Oncoprotein Monoclonal Antibodies
por: Hu, Renjian, et al.
Publicado: (2020)

A novel role of the aryl hydrocarbon receptor (AhR) in centrosome amplification - implications for chemoprevention
por: Korzeniewski, Nina, et al.
Publicado: (2010)

The balance of Polo-like kinase 1 in tumorigenesis
por: Lu, Lin-Yu, et al.
Publicado: (2009)

The CINs of Polo-Like Kinase 1 in Cancer
por: Cunningham, Chelsea E., et al.
Publicado: (2020)

HPV16 E7 oncoprotein test as a triage strategy for HPV16-positive women in cervical cancer screening: long-term follow-up outcome
por: Wang, Xinmei, et al.
Publicado: (2023)

HPV16 E5 deregulates the autophagic process in human keratinocytes
por: Belleudi, Francesca, et al.
Publicado: (2015)

Insulin Resistance Promotes Parkinson’s Disease through Aberrant Expression of α-Synuclein, Mitochondrial Dysfunction, and Deregulation of the Polo-Like Kinase 2 Signaling
por: Hong, Chien-Tai, et al.
Publicado: (2020)

Retinoblastoma-independent antiproliferative activity of novel intracellular antibodies against the E7 oncoprotein in HPV 16-positive cells
por: Accardi, Luisa, et al.
Publicado: (2011)

Intrabodies targeting human papillomavirus 16 E6 and E7 oncoproteins for therapy of established HPV-associated tumors
por: Paolini, Francesca, et al.
Publicado: (2021)

Manipulation of Epithelial Differentiation by HPV Oncoproteins
por: White, Elizabeth A.
Publicado: (2019)

Effects of human papillomavirus (HPV) type 16 oncoproteins on the expression of involucrin in human keratinocytes
por: Gyöngyösi, Eszter, et al.
Publicado: (2012)

An RNA Aptamer Targets the PDZ-Binding Motif of the HPV16 E6 Oncoprotein
por: Belyaeva, Tamara A., et al.
Publicado: (2014)

HPV16 Oncoproteins Promote Cervical Cancer Invasiveness by Upregulating Specific Matrix Metalloproteinases
por: Kaewprag, Jittranan, et al.
Publicado: (2013)

Polo-like kinase-1 in DNA damage response
por: Hyun, Sun-Yi, et al.
Publicado: (2014)

Polo-like kinase 1 as target for cancer therapy
por: Weiß, Lily, et al.
Publicado: (2012)

Playing POLO-like kinase in NRAS mutant melanoma
por: Chen, Hsin-Yi, et al.
Publicado: (2015)

Role for polo-like kinase 4 in mediation of cytokinesis
por: Press, Michael F., et al.
Publicado: (2019)

Polo-Like Kinase 2: From Principle to Practice
por: Zhang, Chuanyong, et al.
Publicado: (2022)

Polo-like kinase 1 promotes pulmonary hypertension
por: Chen, Rongrong, et al.
Publicado: (2023)

Hypoxia inducible factor-1 alpha expression is increased in infected positive HPV16 DNA oral squamous cell carcinoma and positively associated with HPV16 E7 oncoprotein
por: Rodolico, Vito, et al.
Publicado: (2011)

Cannot write session to /tmp/vufind_sessions/sess_aab6qhav1geu0ggdkfra8rc2io