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A Novel Anti-CEACAM5 Monoclonal Antibody, CC4, Suppresses Colorectal Tumor Growth and Enhances NK Cells-Mediated Tumor Immunity

Carcinoembryonic antigen (CEA, CEACAM5, and CD66e) has been found to be associated with various types of cancers, particularly colorectal carcinoma, and developed to be a molecular target for cancer diagnosis and therapy. In present study, we generated a novel anti-CEACAM5 monoclonal antibody, namel...

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Detalles Bibliográficos
Autores principales: Zheng, Chaogu, Feng, Jing, Lu, Di, Wang, Ping, Xing, Shu, Coll, Jean-Luc, Yang, Dongling, Yan, Xiyun
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2011
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3120848/
https://www.ncbi.nlm.nih.gov/pubmed/21731662
http://dx.doi.org/10.1371/journal.pone.0021146