Functional Role of Dimerization of Human Peptidylarginine Deiminase 4 (PAD4)

Peptidylarginine deiminase 4 (PAD4) is a homodimeric enzyme that catalyzes Ca(2+)-dependent protein citrullination, which results in the conversion of arginine to citrulline. This paper demonstrates the functional role of dimerization in the regulation of PAD4 activity. To address this question, we...

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Detalles Bibliográficos
Autores principales: Liu, Yi-Liang, Chiang, Yu-Hsiu, Liu, Guang-Yaw, Hung, Hui-Chih
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2011
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3120853/
https://www.ncbi.nlm.nih.gov/pubmed/21731701
http://dx.doi.org/10.1371/journal.pone.0021314

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3120853/
https://www.ncbi.nlm.nih.gov/pubmed/21731701
http://dx.doi.org/10.1371/journal.pone.0021314

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