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Functional Role of Dimerization of Human Peptidylarginine Deiminase 4 (PAD4)
Peptidylarginine deiminase 4 (PAD4) is a homodimeric enzyme that catalyzes Ca(2+)-dependent protein citrullination, which results in the conversion of arginine to citrulline. This paper demonstrates the functional role of dimerization in the regulation of PAD4 activity. To address this question, we...
| Autores principales: | , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
Public Library of Science
2011
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3120853/ https://www.ncbi.nlm.nih.gov/pubmed/21731701 http://dx.doi.org/10.1371/journal.pone.0021314 |