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MicroRNA Expression and Clinical Outcome of Small Cell Lung Cancer

The role of microRNAs in small-cell lung carcinoma (SCLC) is largely unknown. miR-34a is known as a p53 regulated tumor suppressor microRNA in many cancer types. However, its therapeutic implication has never been studied in SCLC, a cancer type with frequent dysfunction of p53. We investigated the e...

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Detalles Bibliográficos
Autores principales: Lee, Jih-Hsiang, Voortman, Johannes, Dingemans, Anne-Marie C., Voeller, Donna M., Pham, Trung, Wang, Yisong, Giaccone, Giuseppe
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2011
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3120860/
https://www.ncbi.nlm.nih.gov/pubmed/21731696
http://dx.doi.org/10.1371/journal.pone.0021300