Reduced Bone Mass and Muscle Strength in Male 5α-Reductase Type 1 Inactivated Mice

Androgens are important regulators of bone mass but the relative importance of testosterone (T) versus dihydrotestosterone (DHT) for the activation of the androgen receptor (AR) in bone is unknown. 5α-reductase is responsible for the irreversible conversion of T to the more potent AR activator DHT....

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Detalles Bibliográficos
Autores principales: Windahl, Sara H., Andersson, Niklas, Börjesson, Anna E., Swanson, Charlotte, Svensson, Johan, Movérare-Skrtic, Sofia, Sjögren, Klara, Shao, Ruijin, Lagerquist, Marie K., Ohlsson, Claes
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2011
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3120862/
https://www.ncbi.nlm.nih.gov/pubmed/21731732
http://dx.doi.org/10.1371/journal.pone.0021402

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3120862/
https://www.ncbi.nlm.nih.gov/pubmed/21731732
http://dx.doi.org/10.1371/journal.pone.0021402

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