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Reduced Bone Mass and Muscle Strength in Male 5α-Reductase Type 1 Inactivated Mice
Androgens are important regulators of bone mass but the relative importance of testosterone (T) versus dihydrotestosterone (DHT) for the activation of the androgen receptor (AR) in bone is unknown. 5α-reductase is responsible for the irreversible conversion of T to the more potent AR activator DHT....
| Autores principales: | , , , , , , , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
Public Library of Science
2011
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3120862/ https://www.ncbi.nlm.nih.gov/pubmed/21731732 http://dx.doi.org/10.1371/journal.pone.0021402 |