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Insulin-Regulated Srebp-1c and Pck1 mRNA Expression in Primary Hepatocytes from Zucker Fatty but Not Lean Rats Is Affected by Feeding Conditions

Insulin regulates the transcription of genes for hepatic glucose and lipid metabolism. We hypothesized that this action may be impaired in hepatocytes from insulin resistant animals. Primary hepatocytes from insulin sensitive Zucker lean (ZL) and insulin resistant Zucker fatty (ZF) rats in ad libitu...

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Detalles Bibliográficos
Autores principales: Zhang, Yan, Chen, Wei, Li, Rui, Li, Yang, Ge, Yuebin, Chen, Guoxun
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2011
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3120864/
https://www.ncbi.nlm.nih.gov/pubmed/21731709
http://dx.doi.org/10.1371/journal.pone.0021342