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The Effects of Cyclophosphamide on Hippocampal Cell Proliferation and Spatial Working Memory in Rat

Cyclophosphamide (CP) is a chemotherapy used in combinations that are associated with cognitive impairment. In the present study male Lister-hooded rats (n = 12) were used to investigate the effects of chronic administration of CP (30mg/kg, 7 i.v. doses, or an equivalent volume of saline) on perform...

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Detalles Bibliográficos
Autores principales: Lyons, Laura, ELBeltagy, Maha, Bennett, Geoffrey, Wigmore, Peter
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2011
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3120875/
https://www.ncbi.nlm.nih.gov/pubmed/21731752
http://dx.doi.org/10.1371/journal.pone.0021445