Co-Localization of the Oncogenic Transcription Factor MYCN and the DNA Methyl Binding Protein MeCP2 at Genomic Sites in Neuroblastoma

BACKGROUND: MYCN is a transcription factor that is expressed during the development of the neural crest and its dysregulation plays a major role in the pathogenesis of pediatric cancers such as neuroblastoma, medulloblastoma and rhabdomyosarcoma. MeCP2 is a CpG methyl binding protein which has been...

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Detalles Bibliográficos
Autores principales: Murphy, Derek M., Buckley, Patrick G., Das, Sudipto, Watters, Karen M., Bryan, Kenneth, Stallings, Raymond L.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2011
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3120883/
https://www.ncbi.nlm.nih.gov/pubmed/21731748
http://dx.doi.org/10.1371/journal.pone.0021436

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3120883/
https://www.ncbi.nlm.nih.gov/pubmed/21731748
http://dx.doi.org/10.1371/journal.pone.0021436

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