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DBAC: A simple prediction method for protein binding hot spots based on burial levels and deeply buried atomic contacts

BACKGROUND: A protein binding hot spot is a cluster of residues in the interface that are energetically important for the binding of the protein with its interaction partner. Identifying protein binding hot spots can give useful information to protein engineering and drug design, and can also deepen...

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Detalles Bibliográficos
Autores principales: Li, Zhenhua, Wong, Limsoon, Li, Jinyan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2011
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3121121/
https://www.ncbi.nlm.nih.gov/pubmed/21689480
http://dx.doi.org/10.1186/1752-0509-5-S1-S5