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DBAC: A simple prediction method for protein binding hot spots based on burial levels and deeply buried atomic contacts
BACKGROUND: A protein binding hot spot is a cluster of residues in the interface that are energetically important for the binding of the protein with its interaction partner. Identifying protein binding hot spots can give useful information to protein engineering and drug design, and can also deepen...
Autores principales: | Li, Zhenhua, Wong, Limsoon, Li, Jinyan |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2011
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3121121/ https://www.ncbi.nlm.nih.gov/pubmed/21689480 http://dx.doi.org/10.1186/1752-0509-5-S1-S5 |
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