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Transcriptional Profiling of Diabetic Neuropathy in the BKS db/db Mouse: A Model of Type 2 Diabetes

OBJECTIVE: A better understanding of the molecular mechanisms underlying the development and progression of diabetic neuropathy (DN) is essential for the design of mechanism-based therapies. We examined changes in global gene expression to define pathways regulated by diabetes in peripheral nerve. R...

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Detalles Bibliográficos
Autores principales: Pande, Manjusha, Hur, Junguk, Hong, Yu, Backus, Carey, Hayes, John M., Oh, Sang Su, Kretzler, Matthias, Feldman, Eva L.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Diabetes Association 2011
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3121428/
https://www.ncbi.nlm.nih.gov/pubmed/21617178
http://dx.doi.org/10.2337/db10-1541