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Inhibition of Plasminogen Activator Inhibitor-1 Restores Skeletal Muscle Regeneration in Untreated Type 1 Diabetic Mice
OBJECTIVE: Type 1 diabetes leads to impairments in growth, function, and regenerative capacity of skeletal muscle; however, the underlying mechanisms have not been clearly defined. RESEARCH DESIGN AND METHODS: With the use of Ins2(WT/C96Y) mice (model of adolescent-onset type 1 diabetes), muscle reg...
Autores principales: | , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
American Diabetes Association
2011
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3121432/ https://www.ncbi.nlm.nih.gov/pubmed/21593201 http://dx.doi.org/10.2337/db11-0007 |