Inhibition of Plasminogen Activator Inhibitor-1 Restores Skeletal Muscle Regeneration in Untreated Type 1 Diabetic Mice

OBJECTIVE: Type 1 diabetes leads to impairments in growth, function, and regenerative capacity of skeletal muscle; however, the underlying mechanisms have not been clearly defined. RESEARCH DESIGN AND METHODS: With the use of Ins2(WT/C96Y) mice (model of adolescent-onset type 1 diabetes), muscle reg...

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Detalles Bibliográficos
Autores principales: Krause, Matthew P., Moradi, Jasmin, Nissar, Aliyah A., Riddell, Michael C., Hawke, Thomas J.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Diabetes Association 2011
Materias:
Complications
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3121432/
https://www.ncbi.nlm.nih.gov/pubmed/21593201
http://dx.doi.org/10.2337/db11-0007

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