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Real-time Analysis of the Inside-out Regulation of Lymphocyte Function-associated Antigen-1 Revealed Similarities to and Differences from Very Late Antigen-4

Ten years ago, we introduced a fluorescent probe that shed light on the inside-out regulation of one of the major leukocyte integrins, very late antigen-4 (VLA-4, CD49d/CD29). Here we describe the regulation of another leukocyte integrin, lymphocyte function-associated antigen-1 (LFA-1, CD11a/CD18)...

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Detalles Bibliográficos
Autores principales: Chigaev, Alexandre, Smagley, Yelena, Zhang, Yinan, Waller, Anna, Haynes, Mark K., Amit, Or, Wang, Wei, Larson, Richard S., Sklar, Larry A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Society for Biochemistry and Molecular Biology 2011
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3121518/
https://www.ncbi.nlm.nih.gov/pubmed/21515675
http://dx.doi.org/10.1074/jbc.M110.206185