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Transcription factors Sp1 and Sp4 regulate TRPV1 gene expression in rat sensory neurons

BACKGROUND: The capsaicin receptor, transient receptor potential vanilloid type -1 (TRPV1) directs complex roles in signal transduction including the detection of noxious stimuli arising from cellular injury and inflammation. Under pathophysiologic conditions, TRPV1 mRNA and receptor protein express...

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Detalles Bibliográficos
Autores principales: Chu, Catherine, Zavala, Kathryn, Fahimi, Atefeh, Lee, Jessica, Xue, Qing, Eilers, Helge, Schumacher, Mark A
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2011
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3121596/
https://www.ncbi.nlm.nih.gov/pubmed/21645329
http://dx.doi.org/10.1186/1744-8069-7-44