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Anchored FRET sensors detect local caspase activation prior to neuronal degeneration

BACKGROUND: Recent studies indicate local caspase activation in dendrites or axons during development and in neurodegenerative disorders such as Alzheimer's disease (AD). Emerging evidences point to soluble oligomeric amyloid-β peptide as a causative agent in AD. RESULTS: Here we describe the d...

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Detalles Bibliográficos
Autores principales: Figueroa, Ricardo A, Ramberg, Veronica, Gatsinzi, Tom, Samuelsson, Malin, Zhang, Mu, Iverfeldt, Kerstin, Hallberg, Einar
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2011
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3121597/
https://www.ncbi.nlm.nih.gov/pubmed/21605370
http://dx.doi.org/10.1186/1750-1326-6-35