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Anchored FRET sensors detect local caspase activation prior to neuronal degeneration
BACKGROUND: Recent studies indicate local caspase activation in dendrites or axons during development and in neurodegenerative disorders such as Alzheimer's disease (AD). Emerging evidences point to soluble oligomeric amyloid-β peptide as a causative agent in AD. RESULTS: Here we describe the d...
Autores principales: | , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2011
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3121597/ https://www.ncbi.nlm.nih.gov/pubmed/21605370 http://dx.doi.org/10.1186/1750-1326-6-35 |