Molecular interplay between leptin, insulin-like growth factor-1, and β-amyloid in organotypic slices from rabbit hippocampus

BACKGROUND: Evidence shows that the insulin-like growth factor-1 (IGF-1) and leptin reduce β-amyloid (Aβ) production and tau phosphorylation, two major hallmarks of Alzheimer's disease (AD). IGF-1 expression involves the JAK/STAT pathway and the expression of leptin is regulated by the mammalia...

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Detalles Bibliográficos
Autores principales: Marwarha, Gurdeep, Prasanthi, Jaya RP, Schommer, Jared, Dasari, Bhanu, Ghribi, Othman
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2011
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3121598/
https://www.ncbi.nlm.nih.gov/pubmed/21651786
http://dx.doi.org/10.1186/1750-1326-6-41

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3121598/
https://www.ncbi.nlm.nih.gov/pubmed/21651786
http://dx.doi.org/10.1186/1750-1326-6-41

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