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Inhibitory activity of 9-phenylcyclohepta[d]pyrimidinedione derivatives against different strains of HIV-1 as non-nucleoside reverse transcriptase inhibitors

BACKGROUND: The non-nucleoside reverse transcriptase inhibitor (NNRTI), as a major component of the highly active antiretroviral therapy (HAART) to HIV-1 (human immunodeficiency virus type 1) infected patients, required the development of new NNRTIs with improved resistance profile and decreased tox...

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Detalles Bibliográficos
Autores principales: Huang, Yang, Wang, Xiaowei, Yu, Xiaoling, Yuan, Lin, Guo, Ying, Xu, Weisi, Liu, Tiejun, Liu, Junyi, Shao, Yiming, Ma, Liying
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2011
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3121703/
https://www.ncbi.nlm.nih.gov/pubmed/21569631
http://dx.doi.org/10.1186/1743-422X-8-230