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Inhibitory activity of 9-phenylcyclohepta[d]pyrimidinedione derivatives against different strains of HIV-1 as non-nucleoside reverse transcriptase inhibitors
BACKGROUND: The non-nucleoside reverse transcriptase inhibitor (NNRTI), as a major component of the highly active antiretroviral therapy (HAART) to HIV-1 (human immunodeficiency virus type 1) infected patients, required the development of new NNRTIs with improved resistance profile and decreased tox...
Autores principales: | Huang, Yang, Wang, Xiaowei, Yu, Xiaoling, Yuan, Lin, Guo, Ying, Xu, Weisi, Liu, Tiejun, Liu, Junyi, Shao, Yiming, Ma, Liying |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2011
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3121703/ https://www.ncbi.nlm.nih.gov/pubmed/21569631 http://dx.doi.org/10.1186/1743-422X-8-230 |
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