Mutation of the elongin C binding domain of human respiratory syncytial virus non-structural protein 1 (NS1) results in degradation of NS1 and attenuation of the virus

BACKGROUND: Human respiratory syncytial virus (RSV) is an important cause of lower respiratory tract disease in the paediatic population, immunocompromised individuals and the elderly worldwide. However, despite global efforts over the past several decades there are no commercially available vaccine...

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Detalles Bibliográficos
Autores principales: Straub, Claire P, Lau, Wei-Har, Preston, Faith M, Headlam, Madeleine J, Gorman, Jeffery J, Collins, Peter L, Spann, Kirsten M
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2011
Materias:
Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3121706/
https://www.ncbi.nlm.nih.gov/pubmed/21600055
http://dx.doi.org/10.1186/1743-422X-8-252

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3121706/
https://www.ncbi.nlm.nih.gov/pubmed/21600055
http://dx.doi.org/10.1186/1743-422X-8-252

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