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Multi tyrosine kinase inhibitor dasatinib as novel cause of severe pre-capillary pulmonary hypertension?

BACKGROUND: Pulmonary hypertension (PH) is a life-threatening disease with poor prognosis. Encouraging efforts have been made to target the main vasoproliferative aspects of the disease. Promising emerging therapeutics are tyrosine kinase inhibitors such as imatinib. CASE PRESENTATION: Here, we disc...

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Detalles Bibliográficos
Autores principales: Hennigs, Jan K, Keller, Gunhild, Baumann, Hans Jörg, Honecker, Friedemann, Kluge, Stefan, Bokemeyer, Carsten, Brümmendorf, Tim H, Klose, Hans
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2011
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3121732/
https://www.ncbi.nlm.nih.gov/pubmed/21605451
http://dx.doi.org/10.1186/1471-2466-11-30