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Deterministic and Stochastic Allele Specific Gene Expression in Single Mouse Blastomeres

Stochastic and deterministic allele specific gene expression (ASE) might influence single cell phenotype, but the extent and nature of the phenomenon at the onset of early mouse development is unknown. Here we performed single cell RNA-Seq analysis of single blastomeres of mouse embryos, which revea...

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Detalles Bibliográficos
Autores principales: Tang, Fuchou, Barbacioru, Catalin, Nordman, Ellen, Bao, Siqin, Lee, Caroline, Wang, Xiaohui, Tuch, Brian B., Heard, Edith, Lao, Kaiqin, Surani, M. Azim
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2011
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3121735/
https://www.ncbi.nlm.nih.gov/pubmed/21731673
http://dx.doi.org/10.1371/journal.pone.0021208