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Control of Centrin Stability by Aurora A

Aurora A is an oncogenic serine/threonine kinase which can cause cell transformation and centrosome amplification when over-expressed. Human breast tumors show excess Aurora A and phospho-centrin in amplified centrosomes. Here, we show that Aurora A mediates the phosphorylation of and localizes with...

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Detalles Bibliográficos
Autores principales: Lukasiewicz, Kara B., Greenwood, Tammy M., Negron, Vivian C., Bruzek, Amy K., Salisbury, Jeffrey L., Lingle, Wilma L.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2011
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3121746/
https://www.ncbi.nlm.nih.gov/pubmed/21731694
http://dx.doi.org/10.1371/journal.pone.0021291