Redundant Mechanisms Prevent Mitotic Entry Following Replication Arrest in the Absence of Cdc25 Hyper-Phosphorylation in Fission Yeast

Following replication arrest the Cdc25 phosphatase is phosphorylated and inhibited by Cds1. It has previously been reported that expressing Cdc25 where 9 putative amino-terminal Cds1 phosphorylation sites have been substituted to alanine results in bypass of the DNA replication checkpoint. However,...

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Detalles Bibliográficos
Autores principales: Frazer, Corey, Young, Paul G.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2011
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3121752/
https://www.ncbi.nlm.nih.gov/pubmed/21731711
http://dx.doi.org/10.1371/journal.pone.0021348

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3121752/
https://www.ncbi.nlm.nih.gov/pubmed/21731711
http://dx.doi.org/10.1371/journal.pone.0021348

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