Short-Term Serum-Free Culture Reveals that Inhibition of Gsk3β Induces the Tumor-Like Growth of Mouse Embryonic Stem Cells

Here, we present evidence that the tumor-like growth of mouse embryonic stem cells (mESCs) is suppressed by short-term serum-free culture, which is reversed by pharmacological inhibition of Gsk3β. Mouse ESCs maintained under standard conditions using fetal bovine serum (FBS) were cultured in a uniqu...

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Detalles Bibliográficos
Autores principales: Li, Yanzhen, Yokohama-Tamaki, Tamaki, Tanaka, Tetsuya S.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2011
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3121758/
https://www.ncbi.nlm.nih.gov/pubmed/21731714
http://dx.doi.org/10.1371/journal.pone.0021355

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3121758/
https://www.ncbi.nlm.nih.gov/pubmed/21731714
http://dx.doi.org/10.1371/journal.pone.0021355

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