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Integrating 5-Hydroxymethylcytosine into the Epigenomic Landscape of Human Embryonic Stem Cells

Covalent modification of DNA distinguishes cellular identities and is crucial for regulating the pluripotency and differentiation of embryonic stem (ES) cells. The recent demonstration that 5-methylcytosine (5-mC) may be further modified to 5-hydroxymethylcytosine (5-hmC) in ES cells has revealed a...

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Detalles Bibliográficos
Autores principales: Szulwach, Keith E., Li, Xuekun, Li, Yujing, Song, Chun-Xiao, Han, Ji Woong, Kim, SangSung, Namburi, Sandeep, Hermetz, Karen, Kim, Julie J., Rudd, M. Katharine, Yoon, Young-Sup, Ren, Bing, He, Chuan, Jin, Peng
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2011
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3121778/
https://www.ncbi.nlm.nih.gov/pubmed/21731508
http://dx.doi.org/10.1371/journal.pgen.1002154