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Local Absence of Secondary Structure Permits Translation of mRNAs that Lack Ribosome-Binding Sites

The initiation of translation is a fundamental and highly regulated process in gene expression. Translation initiation in prokaryotic systems usually requires interaction between the ribosome and an mRNA sequence upstream of the initiation codon, the so-called ribosome-binding site (Shine-Dalgarno s...

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Detalles Bibliográficos
Autores principales: Scharff, Lars B., Childs, Liam, Walther, Dirk, Bock, Ralph
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2011
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3121790/
https://www.ncbi.nlm.nih.gov/pubmed/21731509
http://dx.doi.org/10.1371/journal.pgen.1002155