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Contribution of Intrinsic Reactivity of the HIV-1 Envelope Glycoproteins to CD4-Independent Infection and Global Inhibitor Sensitivity

Human immunodeficiency virus (HIV-1) enters cells following sequential activation of the high-potential-energy viral envelope glycoprotein trimer by target cell CD4 and coreceptor. HIV-1 variants differ in their requirements for CD4; viruses that can infect coreceptor-expressing cells that lack CD4...

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Detalles Bibliográficos
Autores principales: Haim, Hillel, Strack, Bettina, Kassa, Aemro, Madani, Navid, Wang, Liping, Courter, Joel R., Princiotto, Amy, McGee, Kathleen, Pacheco, Beatriz, Seaman, Michael S., Smith, Amos B., Sodroski, Joseph
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2011
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3121797/
https://www.ncbi.nlm.nih.gov/pubmed/21731494
http://dx.doi.org/10.1371/journal.ppat.1002101