Molecular Implication of PP2A and Pin1 in the Alzheimer's Disease Specific Hyperphosphorylation of Tau

BACKGROUND: Tau phosphorylation and dephosphorylation regulate in a poorly understood manner its physiological role of microtubule stabilization, and equally its integration in Alzheimer disease (AD) related fibrils. A specific phospho-pattern will result from the balance between kinases and phospha...

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Detalles Bibliográficos
Autores principales: Landrieu, Isabelle, Smet-Nocca, Caroline, Amniai, Laziza, Louis, Justin Vijay, Wieruszeski, Jean-Michel, Goris, Jozef, Janssens, Veerle, Lippens, Guy
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2011
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3121875/
https://www.ncbi.nlm.nih.gov/pubmed/21731772
http://dx.doi.org/10.1371/journal.pone.0021521

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3121875/
https://www.ncbi.nlm.nih.gov/pubmed/21731772
http://dx.doi.org/10.1371/journal.pone.0021521

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