Mycobacterium tuberculosis Uses Host Triacylglycerol to Accumulate Lipid Droplets and Acquires a Dormancy-Like Phenotype in Lipid-Loaded Macrophages

Two billion people are latently infected with Mycobacterium tuberculosis (Mtb). Mtb-infected macrophages are likely to be sequestered inside the hypoxic environments of the granuloma and differentiate into lipid-loaded macrophages that contain triacylglycerol (TAG)-filled lipid droplets which may pr...

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Detalles Bibliográficos
Autores principales: Daniel, Jaiyanth, Maamar, Hédia, Deb, Chirajyoti, Sirakova, Tatiana D., Kolattukudy, Pappachan E.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2011
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3121879/
https://www.ncbi.nlm.nih.gov/pubmed/21731490
http://dx.doi.org/10.1371/journal.ppat.1002093

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3121879/
https://www.ncbi.nlm.nih.gov/pubmed/21731490
http://dx.doi.org/10.1371/journal.ppat.1002093

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