Highly Pathogenic Avian Influenza Virus H5N1 Infects Alveolar Macrophages without Virus Production or Excessive TNF-Alpha Induction

Highly pathogenic avian influenza virus (HPAIV) of the subtype H5N1 causes severe, often fatal pneumonia in humans. The pathogenesis of HPAIV H5N1 infection is not completely understood, although the alveolar macrophage (AM) is thought to play an important role. HPAIV H5N1 infection of macrophages c...

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Detalles Bibliográficos
Autores principales: van Riel, Debby, Leijten, Lonneke M. E., van der Eerden, Menno, Hoogsteden, Henk C., Boven, Leonie A., Lambrecht, Bart N., Osterhaus, Albert D. M. E., Kuiken, Thijs
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2011
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3121882/
https://www.ncbi.nlm.nih.gov/pubmed/21731493
http://dx.doi.org/10.1371/journal.ppat.1002099

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3121882/
https://www.ncbi.nlm.nih.gov/pubmed/21731493
http://dx.doi.org/10.1371/journal.ppat.1002099

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