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YB-1 evokes susceptibility to cancer through cytokinesis failure, mitotic dysfunction, and HER2 amplification

Y-box binding protein-1 (YB-1) expression in the mammary gland promotes breast carcinoma that demonstrates a high degree of genomic instability. In the present study, we developed a model of premalignancy to characterize the role of this gene during breast cancer initiation and early progression. An...

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Detalles Bibliográficos
Autores principales: Davies, Alastair H., Barrett, Irene, Pambid, Mary Rose, Hu, Kaiji, Stratford, Anna L., Freeman, Spencer, Berquin, Isabelle M., Pelech, Steven, Hieter, Philip, Maxwell, Christopher, Dunn, Sandra E.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: 2011
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3121916/
https://www.ncbi.nlm.nih.gov/pubmed/21423216
http://dx.doi.org/10.1038/onc.2011.82