Viperin mRNA is a novel target for the human RNase MRP/RNase P endoribonuclease

RNase MRP is a conserved endoribonuclease, in humans consisting of a 267-nucleotide RNA associated with 7–10 proteins. Mutations in its RNA component lead to several autosomal recessive skeletal dysplasias, including cartilage-hair hypoplasia (CHH). Because the known substrates of mammalian RNase MR...

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Detalles Bibliográficos
Autores principales: Mattijssen, Sandy, Hinson, Ella R., Onnekink, Carla, Hermanns, Pia, Zabel, Bernhard, Cresswell, Peter, Pruijn, Ger J. M.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: SP Birkhäuser Verlag Basel 2010
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3121944/
https://www.ncbi.nlm.nih.gov/pubmed/21053045
http://dx.doi.org/10.1007/s00018-010-0568-3

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3121944/
https://www.ncbi.nlm.nih.gov/pubmed/21053045
http://dx.doi.org/10.1007/s00018-010-0568-3

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