Phenethyl isothiocyanate exhibits antileukemic activity in vitro and in vivo by inactivation of Akt and activation of JNK pathways

Effects of phenethyl isothiocyanate (PEITC) have been investigated in human leukemia cells (U937, Jurkat, and HL-60) as well as in primary human acute myeloid leukemia (AML) cells in relation to apoptosis and cell signaling events. Exposure of cells to PEITC resulted in pronounced increase in the ac...

Descripción completa

Detalles Bibliográficos
Autores principales: Gao, N, Budhraja, A, Cheng, S, Liu, E-H, Chen, J, Yang, Z, Chen, D, Zhang, Z, Shi, X
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2011
Materias:
Original Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3122055/
https://www.ncbi.nlm.nih.gov/pubmed/21472003
http://dx.doi.org/10.1038/cddis.2011.22

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3122055/
https://www.ncbi.nlm.nih.gov/pubmed/21472003
http://dx.doi.org/10.1038/cddis.2011.22

Ejemplares similares