Cargando…
Metabolic stress promotes renal tubular inflammation by triggering the unfolded protein response
The renal epithelium contributes to the development of inflammation during ischemic injury. Ischemia induces endoplasmic reticulum (ER) stress and activates the unfolded protein response (UPR). Ischemic tissues generate distress signals and inflammation that activates fibrogenesis and may promote ad...
Autores principales: | , , , , , , |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group
2011
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3122058/ https://www.ncbi.nlm.nih.gov/pubmed/21490675 http://dx.doi.org/10.1038/cddis.2011.26 |