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Metabolic stress promotes renal tubular inflammation by triggering the unfolded protein response

The renal epithelium contributes to the development of inflammation during ischemic injury. Ischemia induces endoplasmic reticulum (ER) stress and activates the unfolded protein response (UPR). Ischemic tissues generate distress signals and inflammation that activates fibrogenesis and may promote ad...

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Detalles Bibliográficos
Autores principales: Fougeray, S, Bouvier, N, Beaune, P, Legendre, C, Anglicheau, D, Thervet, E, Pallet, N
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2011
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3122058/
https://www.ncbi.nlm.nih.gov/pubmed/21490675
http://dx.doi.org/10.1038/cddis.2011.26