Calpain-mediated cleavage of Beclin-1 and autophagy deregulation following retinal ischemic injury in vivo

Autophagy is the major intracellular degradation pathway that regulates long-lived proteins and organelles turnover. This process occurs at basal levels in all cells but it is rapidly upregulated in response to starvation and cellular stress. Although being recently implicated in neurodegeneration,...

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Detalles Bibliográficos
Autores principales: Russo, R, Berliocchi, L, Adornetto, A, Varano, G P, Cavaliere, F, Nucci, C, Rotiroti, D, Morrone, L A, Bagetta, G, Corasaniti, M T
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2011
Materias:
Original Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3122060/
https://www.ncbi.nlm.nih.gov/pubmed/21490676
http://dx.doi.org/10.1038/cddis.2011.29

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3122060/
https://www.ncbi.nlm.nih.gov/pubmed/21490676
http://dx.doi.org/10.1038/cddis.2011.29

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