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Calpain-mediated cleavage of Beclin-1 and autophagy deregulation following retinal ischemic injury in vivo
Autophagy is the major intracellular degradation pathway that regulates long-lived proteins and organelles turnover. This process occurs at basal levels in all cells but it is rapidly upregulated in response to starvation and cellular stress. Although being recently implicated in neurodegeneration,...
| Autores principales: | , , , , , , , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
Nature Publishing Group
2011
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3122060/ https://www.ncbi.nlm.nih.gov/pubmed/21490676 http://dx.doi.org/10.1038/cddis.2011.29 |