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K(Ca)2 channels activation prevents [Ca(2+)](i) deregulation and reduces neuronal death following glutamate toxicity and cerebral ischemia

Exacerbated activation of glutamate receptor-coupled calcium channels and subsequent increase in intracellular calcium ([Ca(2+)](i)) are established hallmarks of neuronal cell death in acute and chronic neurological diseases. Here we show that pathological [Ca(2+)](i) deregulation occurring after gl...

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Detalles Bibliográficos
Autores principales: Dolga, A M, Terpolilli, N, Kepura, F, Nijholt, I M, Knaus, H-G, D'Orsi, B, Prehn, J H M, Eisel, U L M, Plant, T, Plesnila, N, Culmsee, C
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2011
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3122061/
https://www.ncbi.nlm.nih.gov/pubmed/21509037
http://dx.doi.org/10.1038/cddis.2011.30