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The clinical efficacy of -DOPA and STN-DBS share a common marker: reduced GABA content in the motor thalamus

At odd with traditional views, effective sub-thalamic nucleus (STN) deep brain stimulation (DBS), in Parkinson's disease (PD) patients, may increase the discharge rate of the substantia nigra pars reticulata and the internal globus pallidus (GPi), in combination with increased cyclic guanosine...

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Detalles Bibliográficos
Autores principales: Stefani, A, Fedele, E, Vitek, J, Pierantozzi, M, Galati, S, Marzetti, F, Peppe, A, Bassi, M S, Bernardi, G, Stanzione, P
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2011
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3122115/
https://www.ncbi.nlm.nih.gov/pubmed/21544093
http://dx.doi.org/10.1038/cddis.2011.35