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The clinical efficacy of -DOPA and STN-DBS share a common marker: reduced GABA content in the motor thalamus
At odd with traditional views, effective sub-thalamic nucleus (STN) deep brain stimulation (DBS), in Parkinson's disease (PD) patients, may increase the discharge rate of the substantia nigra pars reticulata and the internal globus pallidus (GPi), in combination with increased cyclic guanosine...
Autores principales: | Stefani, A, Fedele, E, Vitek, J, Pierantozzi, M, Galati, S, Marzetti, F, Peppe, A, Bassi, M S, Bernardi, G, Stanzione, P |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group
2011
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3122115/ https://www.ncbi.nlm.nih.gov/pubmed/21544093 http://dx.doi.org/10.1038/cddis.2011.35 |
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