PKCη promotes a proliferation to differentiation switch in keratinocytes via upregulation of p27(Kip1) mRNA through suppression of JNK/c-Jun signaling under stress conditions

To maintain epidermal homeostasis, the balance between keratinocyte proliferation and differentiation is tightly controlled. However, the molecular mechanisms underlying this balance remain unclear. In 3D organotypic coculture with mouse keratinocytes and fibroblasts, the thickness of stratified cel...

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Detalles Bibliográficos
Autores principales: Hara, T, Miyazaki, M, Hakuno, F, Takahashi, S, Chida, K
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2011
Materias:
Original Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3122119/
https://www.ncbi.nlm.nih.gov/pubmed/21593789
http://dx.doi.org/10.1038/cddis.2011.40

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3122119/
https://www.ncbi.nlm.nih.gov/pubmed/21593789
http://dx.doi.org/10.1038/cddis.2011.40

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