Disruption of the ATP-binding Cassette B7 (ABTM-1/ABCB7) Induces Oxidative Stress and Premature Cell Death in Caenorhabditis elegans

X-linked sideroblastic anemia with ataxia (XLSA/A) is a rare inherited disorder characterized by mild anemia and ataxia. XLSA/A is caused by mutations in the ABCB7 gene, which encodes a member of the ATP-binding cassette transporter family. Studies in yeast, mammalian cells, and mice have shown that...

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Detalles Bibliográficos
Autores principales: González-Cabo, Pilar, Bolinches-Amorós, Arantxa, Cabello, Juan, Ros, Sheila, Moreno, Sergio, Baylis, Howard A., Palau, Francesc, Vázquez-Manrique, Rafael P.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Society for Biochemistry and Molecular Biology 2011
Materias:
Molecular Bases of Disease
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3122190/
https://www.ncbi.nlm.nih.gov/pubmed/21464130
http://dx.doi.org/10.1074/jbc.M110.211201

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3122190/
https://www.ncbi.nlm.nih.gov/pubmed/21464130
http://dx.doi.org/10.1074/jbc.M110.211201

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