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Peracetylated 4-Fluoro-glucosamine Reduces the Content and Repertoire of N- and O-Glycans without Direct Incorporation

Prior studies have shown that treatment with the peracetylated 4-fluorinated analog of glucosamine (4-F-GlcNAc) elicits anti-skin inflammatory activity by ablating N-acetyllactosamine (LacNAc), sialyl Lewis X (sLe(X)), and related lectin ligands on effector leukocytes. Based on anti-sLe(X) antibody...

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Detalles Bibliográficos
Autores principales: Barthel, Steven R., Antonopoulos, Aristotelis, Cedeno-Laurent, Filiberto, Schaffer, Lana, Hernandez, Gilberto, Patil, Shilpa A., North, Simon J., Dell, Anne, Matta, Khushi L., Neelamegham, Sriram, Haslam, Stuart M., Dimitroff, Charles J.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Society for Biochemistry and Molecular Biology 2011
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3122228/
https://www.ncbi.nlm.nih.gov/pubmed/21493714
http://dx.doi.org/10.1074/jbc.M110.194597