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TRPV3 and TRPV4 ion channels are not major contributors to mouse heat sensation

BACKGROUND: The discovery of heat-sensitive Transient Receptor Potential Vanilloid (TRPV) ion channels provided a potential molecular explanation for the perception of innocuous and noxious heat stimuli. TRPV1 has a significant role in acute heat nociception and inflammatory heat hyperalgesia. Yet,...

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Detalles Bibliográficos
Autores principales: Huang, Susan M, Li, Xiaoxin, Yu, YinYin, Wang, Juan, Caterina, Michael J
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2011
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3123222/
https://www.ncbi.nlm.nih.gov/pubmed/21586160
http://dx.doi.org/10.1186/1744-8069-7-37