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Mutagenesis Objective Search and Selection Tool (MOSST): an algorithm to predict structure-function related mutations in proteins

BACKGROUND: Functionally relevant artificial or natural mutations are difficult to assess or predict if no structure-function information is available for a protein. This is especially important to correctly identify functionally significant non-synonymous single nucleotide polymorphisms (nsSNPs) or...

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Detalles Bibliográficos
Autores principales: Olivera-Nappa, Alvaro, Andrews, Barbara A, Asenjo, Juan A
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2011
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3123232/
https://www.ncbi.nlm.nih.gov/pubmed/21524307
http://dx.doi.org/10.1186/1471-2105-12-122