Histone deacetylase inhibitors SAHA and sodium butyrate block G1-to-S cell cycle progression in neurosphere formation by adult subventricular cells

BACKGROUND: Histone deacetylases (HDACs) are enzymes that modulate gene expression and cellular processes by deacetylating histones and non-histone proteins. While small molecule inhibitors of HDAC activity (HDACi) are used clinically in the treatment of cancer, pre-clinical treatment models suggest...

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Detalles Bibliográficos
Autores principales: Zhou, Qiong, Dalgard, Clifton L, Wynder, Christopher, Doughty, Martin L
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2011
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3123242/
https://www.ncbi.nlm.nih.gov/pubmed/21615950
http://dx.doi.org/10.1186/1471-2202-12-50

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3123242/
https://www.ncbi.nlm.nih.gov/pubmed/21615950
http://dx.doi.org/10.1186/1471-2202-12-50

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