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Escape is a more common mechanism than avidity reduction for evasion of CD8+ T cell responses in primary human immunodeficiency virus type 1 infection

BACKGROUND: CD8+ T cells play an important role in control of viral replication during acute and early human immunodeficiency virus type 1 (HIV-1) infection, contributing to containment of the acute viral burst and establishment of the prognostically-important persisting viral load. Understanding me...

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Detalles Bibliográficos
Autores principales: Turnbull, Emma L, Baalwa, Joshua, Conrod, Karen E, Wang, Shuyi, Wei, Xiping, Wong, MaiLee, Turner, Joanna, Pellegrino, Pierre, Williams, Ian, Shaw, George M, Borrow, Persephone
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2011
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3123275/
https://www.ncbi.nlm.nih.gov/pubmed/21635736
http://dx.doi.org/10.1186/1742-4690-8-41